Evaluating the Efficacy of Home-Based tDCS for Cancer-Related Cognitive Impairment and Its Moderation by Obesity: A Double-Blind Randomized Controlled Trial.
The goal of this intervention is to investigate whether transcranial Direct Current Stimulation (tDCS) can alleviate Cancer-Related Cognitive Impairment (CRCI) in breast cancer survivors, as measured by changes in brain structures and cognitive performance. To assess the efficacy of tDCS, the investigators will compare outcomes between participants receiving active stimulation and those receiving sham stimulation (a placebo condition where participants believe they are receiving stimulation, but are not). Participants will: * Undergo a baseline MRI session * Receive either active or sham tDCS for six weeks * Undergo a follow-up MRI session * Complete cognitive tests and respond to psychosocial questionnaires before, during, and after the tDCS intervention
• Female
• Over 18 years old
• Diagnosed with primary adult-onset breast cancer within the last 5 years
• Completed all active cancer treatments at least 3 months prior to study participation
• Capable of fulfilling study requirements, including having internet access.
• Fluent in either Finnish or English
• Have normal or corrected vision and hearing
• Right-handed (based on the Edinburgh Handedness Inventory score; Oldfield, 1971)